SECTION 8:
MRI COMPUTER AND WORKSTATION RESOURCES

Facility Manager: Larry Dougherty, Ph.D.
215-349-5274
doughel@uphs.upenn.edu

Equipment
Software
Scanner Software Procedures
MR Image and Raw Data Retrieval
Pulse Sequence Approval


Equipment
The MRI section has three workstations available for general use: "SiemensPC" which is a Dell PC; "barnacle" - SUN Ultra; and "lxsg" - a SGI Octane. The main research workstation is "SiemensPC". User accounts are available to anyone in the section. Users are expected to backup their own directories, the manager only backs-up the system and general use files. Contact Memo Isaac (isaac@rad.upenn.edu, 662-6671) for account infornmtion.


Software
The principal use of SiemensPC is pulse sequence development for the HUP5/HUP6 scanner platforms. The IDEA (Siemens) sequence development environment is available from the Start menu. An online programmer's manual is available for more details. The ICE reconstruction tools and the "Pulsetool" RF development software are also available from within the same menu. Researchers may run this development package on their own PCs by obtaining a license "dongle " from Larry Dougherty. To run this package on their own PCs, users must also obtain a copy of Visual C++.

Siemens source code is provided on an as needed basis by asking Larry Doughetry or Memo Isaac..

For sequence development on the GE LX platform, the EPIC software package resides on "lxsg". Additionally, IDL is available on all three workstations.

Scanner Software Procedures
HUP5* and HUP6* are the designated research scanners. The advanced user options are available on these machines only. Users must be approved by the individual facility manager in order to load pulse sequences. Try not to overload the disk with old sequences. System software should not be loaded or modified by anyone other than Siemens service. Sequences to be used for human use must be approved by CAMRIS prior to use on any human subjects.

HUP 1,2,3,4 are in general not accessible for research. Arrangement to use these systems made be made depending on need and availability.

* The designated research scanners may be subject to change. Whichever scanners are being used for research, the same user account and the responsibilities of the user described here, will be in effect.


MR Image and Raw Data Retrieval
Images are most easily retrieved from HUP5 or HUP6 by using the "Archive to Disk" option. This will load the images onto a CD using the DICOM format.

There are multiple ways to save and retrieve raw data ("measurement data" in Siemens speak). For low volume studies use the following method:

Start (taskbar) -> Run... and type " ideacmdtool".
In cmd tool. Select 3 (Switches)
Select 4 (MeasData2Disk)
This saves a meas.out and MrPort.asc. to Q:\SimMeasData.
Data must be renamed immediately since the next sequence loaded dumps out this data to the same file.

Please make sure to set Data2Disk to "OFF" and exit MATE before leaving
the scanner. Also, it's a good thing to delete the simulation data after
it has been transferred.

The data can be ftp transferred to another computer. Additionally, SIEMENSPC is cross-mounted withh the scanner so that certain folders are available on the SIEMENSOC desktop.

An alternative method is to write a custom reconstruction (ICE routine) that can simply save the data or even transfer it and start a remote reconstruction.


Pulse Sequence Approval

All research pulse sequences that are to be used on human subjects must be approved by the CAMRIS committee prior to human use. Formal approval from the CAMRIS committee or its designee is required before use of a research sequence on any volunteer, including the researchers themselves. Research pulse sequences include those written at HUP or any other institution or corporation. The only sequences that are exempted are those provided by the manufacturer as product and are used within the parameters and protocols for which they were developed. Overriding the design of a product sequence using "control variables" requires CAMRIS approval. Modification of any aspect of an approved sequence requires CAMRIS re-approval before human use is allowed. Additionally, disabling of the RF power monitor is prohibited.

We anticipate that the approval process will only require the documentation of steps that are already being performed by researchers in the development of their sequences, so this process should not represent a burden. Our goal is to formalize and document these procedures. The approval procedure requires the following documents to be submitted to the CAMRIS committee:

1. A brief description of the sequence, paying particular attention to the RF pulse parameters and duty cycle. Include in this description the method of the SAR estimation. SAR may be calculated using the RF pulse structure and code within the pulse sequence, or may be calculated separately. Comparing the new sequence to an existing approved sequence can be a helpful approach.

2. A copy of the actual pulse sequence source code on diskette.

3. A timing diagram of the pulse sequence. This diagram should be generated by the sequence development tools on the workstations. This will document the expected sequence output.. If sub sequences are used (for example, pre-saturation pulses), provide a timing diagram for each sub-sequence. Please use sufficient resolution so as to discern areas of interest (for example, gradient rise times) and turn on axis labeling. Multiple pages may be required to show sufficient detail.

4. A phantom image using the new sequence.

5. The imaging protocol for human use. This may include a range of values to allow flexibility.

When naming the sequences, use a numeric extension that increments on each revision (for example, fgre0, fgre1, … fgreN) so that modifications and their subsequent approval can be documented. Each revision will require CAMRIS approval. Many revisions may qualify for expedited approval as described below.

Documents will be submitted for approval at the CAMRIS meeting following their submission. Sequence changes that do not significantly alter the dB/dt or RF may be reviewed by Larry Dougherty, Hee Kwon Song in an expedited fashion and then presented at the next CAMRIS meeting.

 

 

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2-24-04 LD/ak

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