Postdoctoral Fellow, CMROI, Department of Radiology

Contact

B1 Stellar-Chance Laboratories 422 Curie Blvd. Philadelphia, PA 19104-6100 Tel:(215) 510-8169 Fax: (215) 573-2113 email: anups.minhas@gmail.com

Education

B.Sc. 2000, HP University,Shimla; M.Sc. 2002, GNDU Amritsar; Ph.D. 2008, Indian Institute of Technology Kanpur (IITK)([1])

Work

Research Interests

-Develop novel spin-lock (or T1ρ) MRI applications

-Implement multi-nuclear & multiple-quantum-filtered MRI capability on clinical scanners via: pulse sequence development

-Image processing and data analysis

-Perfusion (DCE and DSC) MRI

The goal of our research is to develop non-invasive and non-destructive MRI techniques for the study of degenerative diseases such as Alzheimer’s Disease and Degenerative Disc Disease. We facilitate timely clinical diagnoses by inventing and improving MRI pulse sequences and hardware. Our multi-nuclear and relaxometric techniques are routinely applied in model systems as well as in clinical research. We maintain active partnerships with faculty from Pathology, Neurology, Orthopedic Surgery and Rheumatology departments and train doctoral candidates from Biophysics and Bioengineering graduate programs at the University of Pennsylvania.

Professional Experience

2008-present: Post-doctoral Researcher, Dept. of Radiology, University of Pennsylvania

2003-2004: Lecturer, Dept. of Mathematics, SSM College Dinanagar, Punjab

Selected Publications

Singh A, Rathore RKS, Haris M, Verma SK, Gupta RK. Improved Bolus Arrival Time and Arterial Input Function Estimation for Tracer Kinetic Analysis in DCE-MRI. J Magn Reson Imaging 29:166–176 (2009)

Singh A, Haris M, Rathore DKS, Purwar A, Sarma MK, Bayu G, Husain N, Rathore RKS, Gupta RK. Quantification of physiological and hemodynamic indices using T1 dynamic contrast enhanced MRI in intracranial mass lesions. J Magn Reson Imaging 2007;26:871-880.

Haris M, Gupta RK, Husain M, Srivastava C, Singh A, Rathore RKS, Saksena S, Behari S, Husain N, Pandey CM, Prasad KN. Assessment of Therapeutic Response on Serial Dynamic Contrast Enhanced MR Imaging in Brain Tuberculomas. Clinical Radiol 2008;63:562-574.

Haris M, Husain N, Singh A, Husain M, Srivastava S, Srivastava C, Behari S, Rathore RKS, Saksena S, Gupta RK. Dynamic contrast enhanced derived cerebral blood volume correlates better with leak correction than with no correction for vascular endothelial growth factor, micro vascular density and grading of astrocytoma. Journal of Computed Assisted Tomography 2008;32;955-965.

Haris M, Gupta RK, Singh A, Rathore DS, Husain N, Husain M, Pandey CM, Srivastava C, Behari S, Singhal U, Rathore RKS. Differentiation of Infective from Neoplastic Brain Lesions by Dynamic Contrast Enhanced MRI. Neuroradiology 2008 2008 Jun;50(6):531-40.

Haris M, Husain N, Singh A, Awasthi R, Rathore RKS, Husain M, Gupta RK. Dynamic Contrast Enhanced (DCE) Derived Transfer coefficient (ktrans) is a Surrogate Marker of Matrix Metalloproteinase 9 (MMP-9) Expression in Brain Tuberculomas. J Magn Reson Imaging 2008;28:588-97.

Rakesh K. Gupta, Mohammad Haris, Nuzhat Husain, Mazhar Husain, Kashi N. Prasad, Mohan Pauliah, Chhitiz Srivastava, Mukesh Tripathi, Manu Rastogi, Sanjay Behari, Anup Singh, Divya Rathore, Ram Kishore S. Rathore. Relative Cerebral Blood Volume Is a Measure of Angiogenesis in Brain Tuberculoma Journal of Computer Assisted Tomography. 31(3):335-341, May/June 2007.