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Opportunities

Trainees and researchers come from a variety of backgrounds, including medicine, bioengineering, biophysics, chemistry, physics, engineering, and mathematics.

The Resource Center excels at educating future scientists on the fundamentals of magnetic resonance theory and application

Both new and established researchers are aided in learning about new developments in the field and to hone their skills for applications within their own research programs.

Investigators may be trained on an individual basis by Resource staff or through group mechanisms such as seminars, courses, and workshops.

As part of their training, students, postdoctoral researchers and fellows are encouraged to present the results of their investigations at international meetings such as International Society of Magnetic Resonance in Medicine (ISMRM), Experimental NMR Conference (ENC), Radiological Society of North America (RSNA), International Conference on Magnetic Resonance and Biological Systems (ICMRBS), Institute of Electrical and Electronic Engineers (IEEE), Human Brain Mapping (HBM), Osteoarthritis Society International (OARSI), Orthopedic Research Society (ORS) and Gordon Research Conferences (GRC), where they can gain firsthand knowledge of the latest scientific innovations. Students receive travel funds through their training grants, the scientific societies, or through travel stipends from the medical school and the Biomedical Graduate Group.

The Resource facility houses over forty desks in a wall-less, cubicle-free environment which promotes open communication and discussion among the Principal Investigator, predoctoral and postdoctoral fellows, and visiting and senior researchers.

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Training

Over the past 24 years, the Research Resource has sponsored the training of 213 young scientists (including 79 in the last funding period). Of these, 16 were MD/PhD students from the medical school, 82 were PhD students from various departments at the university, and the remainder were 58 MD postdoctoral fellows and 57 PhD fellows. The breakdown of trainees over the last funding period are as follows, 1) 4 MD/PHD students, 2) 31 PhD students, 3) 17 MD postdoctoral fellows and 4) 27 PhD postdoctoral fellows.

The faculty of the Research Resource organize and teach several graduate-level courses in MR physics and other basic biomedical sciences. In addition, a biweekly colloquium discussing recent magnetic resonance publications has been organized as a forum for teaching fundamental MR concepts. This colloquium is open to all.

Before, the trainees (driving biomedical projects (DBPs), collaborators and service project users) begin their work at the resource, the resource personnel (TR&D directors and associated personnel) provide customized training in the following aspects

  • Building RF coils and/or gradient coils required for individual research applications.
  • Strategies on pulse sequence development and modifications as demanded by the application and needs of the investigators.
  • Use of image/data processing routines developed at the resource.
  • MR scanner usage training will be provided by going through practical experiments on 7T whole body MRI scanner, 4.7T and 9.4T animal magnets, and 1.5T and 3T clinical research scanners in the Department.
  • The 7T whole-body system is an important teaching tool at the Research Resource. The 7T whole body system is one of only approximately 20 systems world-wide.
  • Use of resource computers for simulation and data processing.
  • Use of facilities for tissue culture and histology.
  • Use of laser facilities for producing hyperpolarized gases.
  • Training in the use of optical imaging instruments and image reconstruction algorithms.

Following initial training described above, the trainees are encouraged to design their own pulse sequences and to build their own RF or gradient coils. Following the training, trainees and researchers are able to design a multitude of experiments ranging from in vitro validation of magnetic resonance pulse sequences with phantoms, biochemical tissue analysis and in vivo human clinical studies.

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Courses offered by our Faculty

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Workshops

As part of dissemination of resource technology the following workshops and symposia have been organized by the resource:

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Upcoming Workshops:

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Past Workshops:

  • 2004 International Workshop on Pulmonary Functional Imaging at PENN

Department of Radiology and MMRRCC
University of Pennsylvania
November 12-14, 2004.
The primary objective of this workshop was to bring together a great variety of knowledge, experience and perspective from a diverse group of investigators. It covered topics ranging from novel imaging techniques to physiology to the clinical application of many new methods.

  • Optical Imaging Retreat-Progress and Clinical Translation of In vivo Imaging

University of Pennsylvania
June 29, 2006

The goal of this workshop was to bring together the state-of-the-art advances in thoracic MR, including hyperpolarized noble gas MRI, as well as the latest developments in other modalities. Recent advances in MR are providing both structural and functional information for comprehensive assessment of lung function. These emerging technologies can be used for the measurement of regional partial pressure of oxygen, regional ventilation, and regional perfusion, which are extremely important parameters in the diagnosis and evaluation of a wide assortment of lung diseases, including emphysema, asthma, and pulmonary embolism. These methods play an important role in thoracic medicine.

The primary objective of this workshop is to bring together the cutting edge researchers in the field of metabolic imaging with an emphasis on the emerging phenomenon of hyperpolarized 13C NMR/MRI. The focus of the meeting included quantitative assessment of metabolism, clinical aspects of molecular processes of cancer and other pathophysiologies, application of hyperpolarized 13C for real-time assessment of molecular processes and metabolism, and standardization of new imagine techniques.

  • 7T Retreat

University of Pennsylvania
Monday, April 16th 2007
The focus of the retreat was to gather potential users of the 7T and to identify potential research projects that would gain the most from 7T and associated software and hardware requirements would be crucial.

  • 2007 In Vivo Optical Imaging Retreat: Progress & Clinical Translation

Thursday, June 28,2007
University of Pennsylvania
Research topics include, but are not limited to, physics and probes, translational research applications, immune imaging and therapy, and breast cancer imaging.

  • NIR Optical Imaging Symposium

August 16th, 2007
University of Pennsylvania
The objective of this symposium was to bring a group of scientists together for the purpose of gaining information on Metabolic Thermodynamics and Thermogenesis.

  • CfN's Diffusion Tensor Imaging Symposium

December 9, 2007
University of Pennsylvania
The overall objective was to review the biophysics of DTI, existing capabilities for DTI data acquisition and analysis, and applications of DTI in neuroscience research.

  • High field imaging

April 9, 2008
University of Pennsylvania
The motivation for the workshop was to highlight the upcoming delivery of the 7T whole body MRI system at Penn. To describe the potential benefits of 7T for basic and clinical neuroscience research. To plan for 7T pilot projects.

  • The Second International Workshop on Hyperpolarized Carbon-13 and its Application to Metabolic Imaging

University of Pennsylvania
January 28-30, 2009.
The primary objective of this workshop was to bring together the cutting edge researchers in the field of metabolic imaging with an emphasis on the emerging phenomenon of hyperpolarized 13C NMR/MRI. Topics covered range from recent advances in hyperpolarized 13C technology, novel imaging molecular and metabolic techniques and clinical applications of new methods.

Hilton Hotel
San Francisco, California
February 14-17, 2009
The primary objective of the planned international Workshop was to bring together researchers of varying backgrounds working on connective tissue microstructure, physiology and function using magnetic resonance imaging techniques and to provide a forum for communication among these diverse groups. The target audience includes biophysicists, bioengineers, chemists, imaging researchers, material scientists, radiologists, and clinicians from related disciplines. The Workshop will also provide an opportunity for participants to get updated on the current status of the MR imaging recent advances of its role in drug development and management of diseases of the musculoskeletal system. The duration of the workshop will be three days. Topics covered include an introduction to the state of the art of musculoskeletal imaging at multiple resolution scales, as well as pre-clinical and clinical applications, with particular emphasis on magnetic resonance imaging and spectroscopy. Organ systems covered include cartilage, bone, inter-vertebral disc and muscle as well as matrix materials such as collagen, proteoglycans and synthetic and engineered biomaterials used for tissue repair.

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Lab Standard Operating Procedures

Please click here to view the MMRRCC SOP manual

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Past Trainees

Listed below are recent MMRRCC trainees and their current positions.

Saroja Adusumilli, MD Assistant Professor of Radiology, University of Michigan, Ann Arbor, MI
Sarma AVS Akella, PhD Assistant Professor, Indian Institute of Technology
Lorilee Arakaki, PhD Research Scientist, University of Washington, Seattle, WA
Jennifer Beers, MA Science Teacher, Master Charter School, Philadelphia, PA
Veerhal Bhoot, DO Radiology Resident, Mercy Catholic Medical Center, Darby, PA
Brian Bronzo, MD Radiology Resident, Massachusetts General Hospital, Boston, MA
David Clayton, PhD Research Associate, Stanford University, Palo Alto, CA
Sridhar Charagundla, MD, PhD Assistant Professor, University of Pennsylvania
Enn-Ling Chen, PhD Assistant Research Professor, Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC
Nancy Cooney, MD Radiology Resident, Jefferson University Hospital
Matt Corbo Graduate Student, University of California, Berkeley, CA
W. Dee Dockery, MD Assistant Professor of Radiology, Director of Cardiovascular MRI, Baylor University, Houston, TX
Uma Duvvuri, MD, PhD Fellow, MD Anderson Cancer Center, Houston, TX
Martin Fischer, PhD Assistant Professor, Department of Chemistry, Duke University, Durham, NC
Douglas Fletcher, PhD Assistant Professor, Uniformed Services University of the Health Sciences, Bethesda, MA
Ari Goldberg, MD, PhD Radiology Resident, University of Pennsylvania, Philadelphia, PA
Jeffrey Goldman, MD Assistant Professor of Radiology, Mount Sinai Medical Center, New York, NY
Maryellyn Gilfeather, MD Assistant Professor of Radiology, University of Utah Health Sciences Center, Salt Lake City, UT
Harvey Hensley, PhD Assistant Professor, Fox Chase Cancer Center, Philadelphia, PA
Justin Hulvershorn, MD, PhD Science Consultant, Seattle, WA
Halvor Juul, PhD Postdoctoral Researcher, Department of Neurology, University of Pennsylvania, Philadelphia, PA
Shuchun (Donald) Li, PhD Research Associate, Department of Physics, University of Pennsylvania
Chia-Shang Jason Liu, MD, PhD Radiology Resident, Albert Einstein Medical Center
Shane Raines Biostatistician, AstraZenaca, Wilmington, DE
Ravinder R. Regatte, PhD Assistant Professor, New York University, New York, NY
Rahim Rizi, PhD Associate Professor of Radiology, University of Pennsylvania
Joseph Roebuck, MD, PhD Radiology Resident, SUNY Downstate
Mark Rosen, MD, PhD Assistant Professor Radiology, University of Pennsylvania
Sloan Rosten, MD Assistant Professor of Radiology, Underwood Mememorial Hospital, Woodbury, NJ
Alan Stolpen, MD, PhD Associate Professor of Radiology, University of Iowa, Iowa City, IA
John C. Schotland, MD, PhD Associate Professor of Bioengineering, University of Pennsylvania, Philadelphia, PA
Dharmesh Tailor, MD, PhD Resident, Department of Radiology, University of Pennsylvania, Philadelphia, PA
Drew Torigian, MD Assistant Professor of Radiology, University of Pennsylvania, Philadelphia, PA
Andrew Wheaton, PhD Scientist, Toshiba Medical Research Institute USA, Cleveland, OH
Linda White-Nunes Associate Professor of Radiologic Sciences, MCP Hahnemann University Hospital, Philadelphia, PA
Quan Yuan Postdoctoral Fellow, M.D. Anderson Cancer Center, Houston, TX


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Previous Speaking Engagements

Please visit our main page detailing the previous speaking engagements by members in our lab

Main Article: Previous Speaking Engagements

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Visiting Scholars

Scientists from other institutions who are involved in metabolic MR studies frequently visit the resource. The visitors may give talks at seminars, but more frequently they interact with the Resource staff on an informal basis. Visiting researchers have also come to the Resource for six-month or one-year sabbaticals. Trainees have the opportunity to speak with these researchers on a personal level. A partial list of recent visitors includes the following:

Mitch Albert Harvard University
Dmitri Artemov Johns Hopkins University
Peter B. Barker Johns Hopkins University
Jorg Barkhausen University Hospital of Essen
Clyde H. Barlow Evergreen State College
Lizann Bolinger National Research Council, Winnipeg, Canada
Paul Bottomley Johns Hopkins University
Deborah Burstein Harvard University
Truman R. Brown Columbia University
George Dodge duPont Hospital for Children, Delaware
Martha Eastlack Arcadia University
Richard Ernst Laboratorium f. Physikalische Chemie, Zurich, Switzerland
Murat Eyuboglu Ankara University, Turkey
Gadi Goelman Haddassah University, Israel
Robert Greeman Beth Israel Deaconess Medical Center
Rolf Gruetter CMRR
Masaru Ishii Johns Hopkins University
Alan Koretsky NIH, NINDS
Martin Kushmerick University of Washington
Martin Leach Royal Marsden Hospital, England
Samuel Lee Temple’s Children’s Hospital
Robert Lenkinski Beth Israel Deaconess Medical Center
Natasha Lisitza Princeton University
Kevin McCully University of Georgia
Alan C. McLaughlin National Institutes of Health, Maryland
Reuben S. Mezrich University of Virginia
Ewald Moser University of Vienna, Austria
James Pekar Georgetown University Medical Center
Jerry L. Prince Johns Hopkins University
Brian Pogue Thayer School of Engineering, Hanover
George Radda Oxford University, England
B.D. Nagesawara Rao Purdue University at Indianapolis
George H. Reed University of Wisconsin, Madison
Bruce Rosen Massachusetts General Hospital
Nadia Rosenthal Massachusetts General Hospital
Larry Siever Mount Sinai School of Medicine
Erik Shapiro NINDS
Meir Shinnar Robert Wood Johnson Medical School
Michael B. Smith Milton S. Hershey Medical Center
Alan Stolpen University of Iowa
Janet Sawicki Lankenau Institute for Medical Research
Bruce Tromberg Beckman Laser Institute
Krista Vandenborne University of Florida
Peter van Zijl Johns Hopkins University
Henning Wackerhage University of Central Lancashire, United Kingdom
Glenn Walter University of Florida
Eric Wickstrom, Thomas Jefferson University

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Last modified May 13, 2009 5:43 pm /
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